TSHR (Thyroid Stimulating Hormone Receptor) is a Protein Coding gene. Diseases associated with TSHR include Hypothyroidism, Congenital, Nongoitrous, 1 and Hyperthyroidism, Familial Gestational. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling.
II. Description
TSHR CHO 報告基因藥靶模型很好的模擬了體內 TSHR 的信號轉導過程,原理見下圖所示。
Figure 1. TSHR CHO 細胞模型原理圖
III. Introduction
Expressed gene:
TSHR
Stability:
32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:
90% FBS+10% DMSO
Culture Medium:
F12K+10%FBS+5μg/ml Puromycin
Mycoplasma Testing:
Negative
Storage:
Liquid nitrogen
Application(s):
Functional assay for TSHR receptor
Transducer:
Gs
IV. Representative Data
Figure 2. Recombinant TSHR CHO stably expressing TSHR.