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hClaudin9(CLDN9)/4T1

CBPG0064

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I. Background    
CLDN9 (Claudin 9) is a Protein Coding gene. Diseases associated with CLDN9 include Deafness, Autosomal Recessive 116 and Hepatitis C Virus.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.     
     
II. Introduction    
Host Cell: 4T1    
Expressed gene: hClaudin9(CLDN9)    
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)    
Freeze Medium: 90% FBS+10% DMSO    
Culture Medium: RPMI-1640+10%FBS+2ug/ml  puromycin    
Mycoplasma Testing: Negative    
Storage: Liquid nitrogen    
     
III. Description of Host Cell Line    
Organism: Mouse    
Tissue: Mammary gland    
Morphology: Epithelial    
Growth Properties: Adherent    
   
IV. Representative Data    

Figure 1. Recombinant hClaudin9(CLDN9)/4T1 stably expressing CLDN9.

 
   

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