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診斷試劑
腫瘤早篩甲基化標(biāo)準(zhǔn)品
遺傳性基因標(biāo)準(zhǔn)品
優(yōu)生優(yōu)育標(biāo)準(zhǔn)品
HLA標(biāo)準(zhǔn)品
數(shù)字PCR
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診斷試劑
diagnosis
Introduction | |
Format | Genomic DNA |
Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
Technical Data | |
DNA Change | c.1200insCC |
AA Change | p.SP400fs |
Mutation type | |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | N/A |
Cosmic ID | N/A |
Chr position(GRCh37) | chr4:1806180 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |